RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
mir-29b
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
qRT-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
MicroRNA-19b reduces hepatic stellate cell proliferation by targeting GRB2 in hepatic fibrosis models in vivo and in vitro as part of the inhibitory effect of estradiol
Year
2015
Function
Mir-29b prevents liver fibrogenesis by inhibiting hsc activation and inducing hsc apoptosis through inhibiting pi3k;Akt pathway.